Belotero is an injectable dermal filler with a hyaluronic acid base. It binds with water, which helps to plump up your skin and make it appear smoother. Over time, your body absorbs the hyaluronic acid in Belotero . It is used to reduce the appearance of lines and folds in facial skin It is FDA-approved to smooth moderate to severe facial wrinkles and folds, such as nasolabial folds